
Find hotels in South Carolina Midlands, SC from CA $86
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in South Carolina Midlands
Family friendly
Check prices for these dates
Our top choices for South Carolina Midlands hotels

Howard Johnson by Wyndham Florence
Howard Johnson by Wyndham FlorenceFlorence
8.6 out of 10, Excellent, (2,597 reviews)
The price is CA $83
CA $93 total
includes taxes & fees
Apr 26 - Apr 27

Holiday Inn Express & Suites Latta by IHG
Holiday Inn Express & Suites Latta by IHGLatta
9.6 out of 10, Exceptional, (568 reviews)
The price is CA $175
CA $191 total
includes taxes & fees
Apr 7 - Apr 8

Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
7.8 out of 10, Good, (1,427 reviews)
The price is CA $110
CA $122 total
includes taxes & fees
Apr 7 - Apr 8

Hampton Inn Rock Hill
Hampton Inn Rock HillRock Hill
9.2 out of 10, Wonderful, (1,001 reviews)
The price is CA $124
CA $138 total
includes taxes & fees
Apr 6 - Apr 7

Best Western Rock Hill
Best Western Rock HillRock Hill
8.6 out of 10, Excellent, (1,003 reviews)
The price is CA $101
CA $112 total
includes taxes & fees
Apr 7 - Apr 8

Park Inn by Radisson Florence, SC
Park Inn by Radisson Florence, SCFlorence
9.0 out of 10, Wonderful, (2,230 reviews)
The price is CA $125
CA $140 total
includes taxes & fees
Mar 29 - Mar 30

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (770 reviews)
The price is CA $169
CA $187 total
includes taxes & fees
Apr 26 - Apr 27

Lexington Expo Hotel by IHG
Lexington Expo Hotel by IHGLexington
9.2 out of 10, Wonderful, (1,004 reviews)
The price is CA $164
CA $182 total
includes taxes & fees
Mar 29 - Mar 30

La Quinta Inn & Suites by Wyndham Rock Hill
La Quinta Inn & Suites by Wyndham Rock HillRock Hill
9.0 out of 10, Wonderful, (1,101 reviews)
The price is CA $123
CA $137 total
includes taxes & fees
Apr 5 - Apr 6

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
La Quinta Inn by Wyndham Columbia SE / Fort JacksonColumbia
7.8 out of 10, Good, (999 reviews)
The price is CA $123
CA $141 total
includes taxes & fees
Apr 5 - Apr 6

Springhill Suites by Marriott Columbia near Fort Jackson
Springhill Suites by Marriott Columbia near Fort JacksonColumbia
9.4 out of 10, Exceptional, (647 reviews)
The price is CA $157
CA $176 total
includes taxes & fees
Apr 26 - Apr 27

Holiday Inn Express Richburg by IHG
Holiday Inn Express Richburg by IHGRichburg
9.2 out of 10, Wonderful, (666 reviews)
The price is CA $136
CA $153 total
includes taxes & fees
Apr 19 - Apr 20

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,000 reviews)
The price is CA $164
CA $182 total
includes taxes & fees
Apr 19 - Apr 20

La Quinta Inn by Wyndham Columbia NE/Fort Jackson
La Quinta Inn by Wyndham Columbia NE/Fort JacksonColumbia
8.8 out of 10, Excellent, (1,920 reviews)
The price is CA $129
CA $145 total
includes taxes & fees
Mar 29 - Mar 30

Spark by Hilton Rock Hill
Spark by Hilton Rock HillRock Hill
9.0 out of 10, Wonderful, (148 reviews)
The price is CA $125
CA $138 total
includes taxes & fees
Apr 8 - Apr 9

Quality Inn & Suites Columbia Harbison
Quality Inn & Suites Columbia HarbisonColumbia
8.6 out of 10, Excellent, (253 reviews)
The price is CA $109
CA $122 total
includes taxes & fees
Apr 26 - Apr 27

Inn on the Square, an Ascend Collection Hotel
Inn on the Square, an Ascend Collection HotelUptown Greenwood
9.2 out of 10, Wonderful, (725 reviews)
The price is CA $180
CA $200 total
includes taxes & fees
Apr 16 - Apr 17

Best Inn of Manning
Best Inn of ManningManning
7.0 out of 10, Good, (20 reviews)
The price is CA $92
CA $103 total
includes taxes & fees
Mar 30 - Mar 31

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,000 reviews)
The price is CA $157
CA $174 total
includes taxes & fees
Apr 19 - Apr 20

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,000 reviews)
The price is CA $198
CA $219 total
includes taxes & fees
Apr 26 - Apr 27
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Vacation Rentals in South Carolina Midlands
Cabin

8.6 out of 10, Excellent, (249 reviews)
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Southeastern United States attractions
Learn more about South Carolina Midlands
With Revolutionary War sites, a charming capital city and lots of kayaking opportunities, this southern region is sure to delight.

Top South Carolina Midlands Hotel Reviews
Recent Reviews in South Carolina Midlands

Hilton Garden Inn Columbia/Harbison
10/10 Excellent
More cheap stays in South Carolina Midlands

Baymont by Wyndham Columbia Northwest
347 Zimalcrest Drive Columbia SC
The price is CA $80 per night from Apr 13 to Apr 14
CA $80
CA $86 total
Apr 13 - Apr 14
includes taxes & fees
5.6/10 (1,002 reviews)
Hotels in South Carolina Midlands with star rating

4 Star Hotels
13 properties
Explore a world of travel with Expedia
- Hotels near Allen University
- B&B in Arcadia Lakes
- Guest Houses in Arcadia Lakes
- Arcadia Lakes Hotels
- Inns in Arcadia Lakes
- Arsenal Hill Hotels
- Hotels near Benedict College
- Apartments in Blythewood
- B&B in Blythewood
- Casino Hotels in Blythewood
- Cheap Hotels in Blythewood
- Luxury Hotels in Blythewood
- Pet-Friendly Hotels in Blythewood
- Blythewood Hotels
- Vacation Homes in Blythewood
- Guest Houses in Cedar Creek
- Columbia Hotels
- Hotels near Columbia Place Mall
- B&B in Dentsville
- Cheap Hotels in Dentsville
- Hotels with a Pool in Dentsville
- Hotels with an Indoor Pool in Dentsville
- Pet-Friendly Hotels in Dentsville
- Dentsville Hotels
- Vacation Homes in Dentsville
- South Carolina Hotels
- Downtown Columbia Hotels
- Eau Claire Hotels
- B&B in Elgin
- Cabin Rentals in Elgin
- Castles in Elgin
- Guest Houses in Elgin
- Cheap Hotels in Elgin
- Elgin Hotels
- Inns in Elgin
- Hotels near First Baptist Church
- Farmstay in Forest Acres
- Cheap Hotels in Forest Acres
- Luxury Hotels in Forest Acres
- Forest Acres Hotels
- Hotels near Fort Jackson
- Hotels near Hilton Field
- Cheap Hotels in Killian
- Lgbt Friendly Hotels in Killian
- Killian Hotels
- Hotels near Koger Center for the Arts
- Pet-Friendly Hotels in Lake Carolina
- Spa Hotels in Lake Carolina
- Lake Carolina Hotels
- Boutique Hotels in Lyon Street
- Motel 6 Hotels in Lyon Street
- Red Roof Inn Hotels in Lyon Street
- Casino Hotels in Melrose Heights
- Spa Hotels in Old Shandon
- Hotels near Palmetto Health Richland Hospital
- Hotels with Free Breakfast in Pinehurst
- Adults Only Resorts & in Rosewood
- Hotels with a Lazy River in Rosewood
- Hotels with Bar in Rosewood
- Hotels with Hot Tubs in Rosewood
- Lgbt Friendly Hotels in Rosewood
- Luxury Hotels in Rosewood
- Pet-Friendly Hotels in Rosewood
- Spa Hotels in Rosewood
- Hotel Wedding Venues Hotels in Rosewood
- Winery Hotels in Rosewood
- Rosewood Hotels
- Sandwood Hotels
- Hotels near Segra Park
- Hotels near Sesquicentennial State Park
- Shandon Hotels
- Hotels near South Carolina State House
- Hotels near Township Auditorium
- Hotels near University of South Carolina
- Beach Hotel Hotels in Waverly
- Hotels with Early Check-in in Waverly
- Oceanfront Hotels in Waverly
- Waverly Hotels
- Farmstay in Woodfield
- Apartments in Woodfield
- B&B in Woodfield
- Beach Hotel Hotels in Woodfield
- Cheap Hotels in Woodfield
- Golf Hotels in Woodfield
- Luxury Hotels in Woodfield
- Pet-Friendly Hotels in Woodfield
- Woodfield Hotels
- Inns in Woodfield

































































































































